Metallic Taste

A metallic taste in the mouth is a common complaint, and can derive from a variety of causes:
  1. Tooth decay, infected tooth, exudate from inflammation, or periodontal disease
  2. Gastroesophageal reflux disease (GERD, Gastric reflux disease, or acid reflux disease), caused by abnormal lower esophageal sphincter, results in leakage of acid from the stomach to esophagus, and continue to the mouth
  3. Upper respiratory condition such as sinusitis
  4. Diabetes
  5. Thrush - oral yeast infection
  6. Oral mucous membrane disease, such as Pemphigoid, Lupus, or Pemphigus Vulgaris
  7. Too much copper in the body
  8. Kidney stone
  9. Dry mouth (Xerostomia)
  10. Burning mouth syndrome
  11. Anemia - pernicious anemia (anemia caused by insufficient B12 to make red blood cells)
  12. Some prescription drugs that cause metallic taste in the mouth:
  • High blood pressure medication, e.g.,
    • AngiotensinII receptor blockers
    • Candesartan (Atacand)
    • Eprosartan(Teveten)
    • Irbesartan (Avapro)
    •  Losartan (Cozaar)
    • Olmesartan (Benicar)
    • Telmisartan (Micardis)
    • Valsartan (Diovan)

  • Heart failure, scleroderma, heart attacks, kidney disease, and migrain medications, ACE inhibitors:
    • Captopril
    • Lisinopril (Prinivil, Zestril)
    • Fosinopril, Enalapril (Vasotec)
    • Trandolapril (Mavik)
    • Quinapril (Accupril)
    • Ramipril (Altace)
    • Benazepril (Lotensin)
    • Moexipril (Univasc)
    • Perindopril (Aceon)

  • Diabetic medication; Metformin

  • Some antibiotics:
    • Metronidazole (Flagyl)
    • Clarithromycin (Biaxin)
    • Trimethoprim-sulfamethoxazole
    • Griseofulvin (for skin infection)
    •  Azithromycin
    • Ethionamide

  • Anti-thyroid medications: 
    • Radioactive iodine
    • Propylthiouracil 
    •  Methimazole

  • Cancer chemotherapy medications:
    • Paclitaxel
    • Vincristine
    • Levamisole
    • Methotrexate
    • Dacarbazine
    • Mechlorethamine
    • Cyclophosphamide
    • Cisplatin
    • Carboplatin

  • Bipolar medication: Lithium

  • Muscle relaxant (Methocarbamol)

  • Rheumatoid Arthritis: Penicillamine