Tylenol® #3

Acetaminophen and codeine combination (Tylenol #3) is a drug used to relieve moderate to severe pain.  Tylenol #3 is in a narcotic class and should not be taken in a large amount or for a longer period than prescribed due to its potential habit forming. Tylenol #3 should be taken with food to prevent upset stomach.

Caution must be taken when prescribe to elderly patients, patients with head injuries, severe kidney or liver disease, hypothyroidism, Addison's disease and acute abdominal problems. Do not prescribe to children under 12 years of age. Prolong use of Tylenol #3 results in tolerance to codeine. During pregnancy, Tylenol with Codeine should not be used close to the expected delivery date and should not be used during nursing.

The usual adult dosage of Tylenol with codeine is 15 mg to 60 mg codeine and 300 to 1000 mg acetaminophen every 4 hours.  Codeine higher than 60 mg may increase undesirable side effects.

Active ingredients in a tablet contain Acetaminophen 300 mg, Codeine Phosphate 30 mg.
Inactive ingredients: Powder cellulose,  Magnesium stearate, Sodium metabisulfite, Pregelatinized corn starch and modified corn starch.

Side effects:
  1. Nausea, vomiting
  2. Constipation
  3. Lightheadedness, fainting
  4. Dizziness or drowsiness
  5. Difficulty breathing, shallow breathing or irregular breathing
  6. Allergic reactions
  7. Elevated mood (Euphoria)
  8. Anxiety (Dysphoria)
  9. Abdominal pain
  10. Itching (Pruritus)
  11. Rash
  12. Low platelet count (Thrombocytopenia)
  13. Decrease in white blood cell granulocytes (Agranulocytosis)
  14. Respiratory depression (on high dose)
  15. Pale, blue lips, fingernails
  16. Seizures
  17. Black stool
  18. Easy bruising or bleeding
  19. Blood found in urine
  20. Swelling at the lips, eyelids, face, or tongue
  21. Blurred vision
  22. Dry mouth

Before taking this pharmaceutical, consider the potential benefits and risks to other alternative options.

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