Fluconazole (Diflucan)

Fluconazole (Diflucan) is a synthetic Triazole antifungal agent (prevent the growth of yeasts and other fungal organisms). Fluconazole is medication for treating candidiasis, infections caused by fungus (yeast) in the mouth, throat, esophagus, blood, bladder, genital.  Fluconazole can also prevent the fungal infection in people with weak immune systems, e.g., patients with cancer treatment, bone marrow transplant, or AIDS. Pregnant women should not take Fluconazole.

Active ingredients
Diflucan tablet contains 50, 100, 150, 200 mg of fluconozole

Inactive ingredients: Povidone, Microcrystalline cellulose, Dibasic calcium phosphate anhydrous, croscarmellose sodium, Dye, Magnesium stearate

Supplied forms of Fluconazole:
  1. 150 mg as a single dose once a day.  The length of the treatment depends on the improvement of the condition
  2. Multiple doses, 200 mg on the first day, follow by 100 mg, once a day for at least 2 weeks
Side effects of Fluconazole:
    1. Nausea, vomiting, dry mouth
    2. Stomach pain
    3. Itching
    4. Loss of appetite, 
    5. Dark urine, clay-colored stools, 
    6. Jaundice (yellowing of the skin or eyes)
    7. Fever, chills, body aches, flu-like symptoms
    8. Severe blistering, peeling, and red skin rash
    9. Easily get bruise or bleeding
    10. Weakness, lack of energy (Asthenia)
    11. Convulsions
    12. Diarrhea, upset stomach
    13. Headache
    14. Dizziness, Seizures
    15. Unpleasant taste in the mouth
    16. Allergic reaction
    17. Hepatitis (inflammation of the liver)
    18. Muscle pain (Myalgia)
    19. Insomnia
    20. Tremor, vertigo, paresthesia (abnormal body sensation: numbness, burning and tingling
    21. Somnolence (sleepiness)
    22. Sweating
    23. Stevens-Johnson syndrome
    24. Alopecia (baldness)
Drugs interaction:
Do not take Fluconazole with Cisapride (Propulsid).  Other common drugs that may affect Fluconazole are:
  1. Blood thinner, e.g., Warfarin (Coumadin, Jantoven)
  2. Antidepressants (Elavil, Vanatrip, Limbritrol, Pamelor)
  3. Cancer medicines
  4. Cholesterol lowering drugs
  5. Heart or blood pressure medicines
  6. Non-steroidal anti-inflammatory drugs (Advil, Motrin, Celebrex, and others)
  7. Oral diabetes medication (Glucotrol, Diabeta, Orinase, and others)
  8. Sedative (Valium, Ativan, Xanax, and others)
  9. Seizure medication (Dilantin, Carbatrol, Tegretol, Depakene
  10. Prednisone (Deltasone, Sterapred)
Carefully consider the potential risks and benefits of this pharmaceutical to other alternative options before using it.

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